Curated Data based on Instance of Characterization
As Synthesized
 
Nanomaterial State:
liquid suspension
Manufacturer:
Dr. Dan Goia (Clarkson University)
Synthesis Method:
reduction of Ag ion in solution by polysaccharide
  • Physico-Chemical Characteristics
  • biological interactions
  • Environmental interactions
Composition
graph
CORE (hover over circle for proportion of material)
arrow Proportion of Nanomaterial:    Not reported
Component 1
Molecular Identity:
Ag

Material Type:
metal
COATING (hover over circle for proportion of material)
arrow Proportion of Nanomaterial:    Not reported
Component 1
Molecular Identity:
polysaccharide
Material Type:
Biological Type:

carbohydrate
As Processed A
 
Nanomaterial State:
powder
Manufacturer:
Dr. Dan Goia (Clarkson University)
Processing Type:
dried
  • Physico-Chemical Characteristics
  • biological interactions
  • Environmental interactions
Particle Size

Mean Diameter:
9.48 nm +/- 4.92 nm
Transmission Electron Microscopy
As Processed B
 
Nanomaterial State:
liquid suspension
Manufacturer:
Dr. Dan Goia (Clarkson University)
Processing Type:
suspended
  • Physico-Chemical Characteristics
  • biological interactions
  • Environmental interactions
Particle Size

Mean Hydrodynamic Diameter:
658 nm
Dynamic Light Scattering
PDI (size):
0.261
Dynamic Light Scattering
Aggregation/Agglomeration State

State:
Aggregated
Dynamic Light Scattering
As Processed C
 
Nanomaterial State:
liquid suspension
Synthesis Method:
10 micrograms NP + Tacaribe virus
Processing Type:
suspended
  • Physico-Chemical Characteristics
  • biological interactions
  • Environmental interactions
Particle Size

Mean Hydrodynamic Diameter:
481 nm
Dynamic Light Scattering
PDI (size):
0.444
Dynamic Light Scattering
Aggregation/Agglomeration State

State:
Aggregated
Dynamic Light Scattering
As Processed D
 
Nanomaterial State:
liquid suspension
Synthesis Method:
50 micrograms NP + Tacaibe virus
Processing Type:
suspended
  • Physico-Chemical Characteristics
  • biological interactions
  • Environmental interactions
Particle Size

Mean Hydrodynamic Diameter:
756 nm
Dynamic Light Scattering
PDI (size):
0.462
Dynamic Light Scattering
Aggregation/Agglomeration State

State:
Aggregated
Dynamic Light Scattering

In Vitro Study 1

Test Subject
Test Subject 1:
Cell Culture Type: cultured cell line
Name: Vero Cells
Strain:
Cell Source:
General Study Details
General:
Test Location: laboratory
Controls Used/Reported: Positive, Negative
Standard Protocol Used: Biocompatibility Assay
Assay Used:
Manufacturer: Promega
Assay Name: MTS assay
Exposure Summary
General:
Method of Exposure: inoculation
Acute or Chronic Exposure: Acute exposure
Intended Dose: 50, 75, 100 µg/mL
Actual Dose:
Frequency of Dosage:
Duration of Exposure / Incubation Time: 24, 48, 192 hours
Duration Between Exposure and Sampling:
Duration Between Exposure and Measurement:
Endpoint
Toxicity:
Cytotoxicity: Reported Qualitatively
Mechanistic Analysis:
Gene Expression:
Protein Expression:
Enzyme Expression:
Cellular Uptake:
Cellular Uptake 1:
Biotransformation:
Biotransformation 1:
Other:
Metabolism:

In Vitro Study 2

Test Subject
Test Subject 1:
Cell Culture Type: cultured cell line
Name: Vero Cells
Strain:
Cell Source:
General Study Details
General:
Test Location: laboratory
Controls Used/Reported: Positive, Negative
Standard Protocol Used: Viral Inhibition Assay
Assay Used:
Manufacturer:
Assay Name:
Exposure Summary
General:
Method of Exposure: inoculation
Acute or Chronic Exposure: Acute exposure
Intended Dose: 0, 1, 5, 10, 25, 50, 100 µg/mL
Actual Dose:
Frequency of Dosage:
Duration of Exposure / Incubation Time: 8 days
Duration Between Exposure and Sampling:
Duration Between Exposure and Measurement:
Endpoint
Toxicity:
Cytotoxicity: Reported Quantitatively
Mechanistic Analysis:
Gene Expression:
Protein Expression:
Enzyme Expression:
Cellular Uptake:
Cellular Uptake 1:
Biotransformation:
Biotransformation 1:
Other:
Metabolism:

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MIAN-specific data are curated from data sources and presented on the nanomaterial details page, below. When available, the original publication link is provided so that you can verify the source data and access data that is outside of the NR MIAN. The NR Descriptor is a high level classification of the nanomaterial based on primary composition and shape.
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Data for physico-chemical characteristics (PCC) and interaction studies are curated when available. Physico-chemical characteristics are curated based upon the Registry’s Minimal Information about Nanomaterials (MIAN). Data from studies are contained on the Biological and Environmental Interaction tab and are summarized using four categories: General Study Details, Test Subject(s), Exposure Summary(s), and Endpoint(s).
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