Curated Data based on Instance of Characterization
As Received
 
Nanomaterial State:
Not Reported
Manufacturer:
Sigma Aldrich
Product Name:
572500
  • Physico-Chemical Characteristics
  • biological interactions
  • Environmental interactions
Particle Size

Size:
0.7 nm
Composition
graph
CORE (hover over circle for proportion of material)
arrow Proportion of Nanomaterial:    Not reported
Component 1
Material Type:
Fullerene/Carbon:

Buckyball
Molecular Identity:
C60

As Processed A
 
Nanomaterial State:
liquid suspension
Processing Type:
suspended, sonicated
  • Physico-Chemical Characteristics
  • biological interactions
  • Environmental interactions
Particle Size

Mean Hydrodynamic Diameter:
Intensity Weighted:
150 - 700 nm
Dynamic Light Scattering
Mean Hydrodynamic Diameter:
Intensity Weighted:
311 nm
Dynamic Light Scattering
As Processed B
 
Nanomaterial State:
powder
  • Physico-Chemical Characteristics
  • biological interactions
  • Environmental interactions
Surface Area

Specific Surface Area:
20 m^2/g
Brunauer, Emmett and Teller Gas Adsorption Analysis
Pore Size:
0 nm
Brunauer, Emmett and Teller Gas Adsorption Analysis
As Processed C
 
Nanomaterial State:
liquid suspension
Processing Type:
suspended, sonicated
  • Physico-Chemical Characteristics
  • biological interactions
  • Environmental interactions

In Vitro Study 1; Cell Viability; LDH Activity

Test Subject
Test Subject 1:
Cell Culture Type: primary cultured cells
Name: Lung Epithelial Cells
Strain: FE1-MML
Cell Source: transgenic Muta Mouse
General Study Details
General:
Test Location: laboratory
Standard Protocol Used: Cytotoxicity
Assay Used:
Manufacturer: Roche, Hvidovre, Denmark)
Assay Name: LDH Activity
Exposure Summary
General:
Method of Exposure: inoculation
Acute or Chronic Exposure: Acute exposure
Intended Dose: 0, 20, 40, 60, 80, 100, 200 µg/mL
Duration of Exposure / Incubation Time: 24, 576 hours
Endpoint
Toxicity:
Cytotoxicity: Reported Quantitatively

In Vitro Study 2; DNA Damage

Test Subject
Test Subject 1:
Cell Culture Type: primary cultured cells
Name: Lung Epithelial Cells
Strain: FE1-MML
Cell Source: transgenic Muta Mouse
General Study Details
General:
Test Location: laboratory
Assay Used:
Assay Name: Comet Assay
Exposure Summary
General:
Method of Exposure: inoculation
Acute or Chronic Exposure: Acute exposure
Intended Dose: 10 µg/mL
Duration of Exposure / Incubation Time: 3 hours
Duration Between Exposure and Measurement: 145 minutes
Endpoint
Other:
DNA Damage: Reported Quantitatively

In Vitro Study 3; Cellular Mutation

Test Subject
Test Subject 1:
Cell Culture Type: primary cultured cells
Name: Lung Epithelial Cells
Strain: FE1-MML
Cell Source: transgenic Muta Mouse
General Study Details
General:
Test Location: laboratory
Controls Used/Reported: Positive, Negative
Standard Protocol Used: Plaque formation
Assay Used:
Manufacturer: lambda Select-cIITM Mutation Detection System for the Big Blue Rodents, Stratagene
Assay Name: Plaque formation
Exposure Summary
General:
Method of Exposure: inoculation
Acute or Chronic Exposure: Acute exposure
Intended Dose: 8 mg/mL
Duration of Exposure / Incubation Time: 576 hours
Duration Between Exposure and Measurement: 72 hours
Endpoint
Toxicity:
Cytotoxicity:
Mechanistic Analysis:
Gene Expression:
Protein Expression:
Enzyme Expression:
Cellular Uptake:
Cellular Uptake 1:
Biotransformation:
Biotransformation 1:
Other:
Cellular Mutation: Reported Quantitatively

In Vitro Study 4; ROS Generation

Test Subject
Test Subject 1:
Cell Culture Type: primary cultured cells
Name: Lung Epithelial Cells
Strain: FE1-MML
Cell Source: transgenic Muta Mouse
General Study Details
General:
Test Location: laboratory
Controls Used/Reported: Positive
Standard Protocol Used: flouresence spectrofluorometry
Exposure Summary
General:
Method of Exposure: inoculation
Acute or Chronic Exposure: Acute exposure
Intended Dose: 2.78, 8.33, 25.00 µg/mL
Duration of Exposure / Incubation Time: 3 hours
Endpoint
Toxicity:
Cytotoxicity:
Mechanistic Analysis:
Gene Expression:
Protein Expression:
Enzyme Expression:
Cellular Uptake:
Cellular Uptake 1:
Biotransformation:
Biotransformation 1:
Other:
ROS Generation: Reported Quantitatively

How well was this nanomaterial characterized? Be the first to comment on the characterization of this nanomaterial.

Comments

No comments found for this nanomaterial.

Leave a Comment

Your Name:*
Your Email:*
Comments:*
Do you think this nanomaterial was well characterized? Yes No
What is 5+5?*
This question is for testing whether you are a human visitor and to prevent automated spam submissions.
* Required
MIAN-specific data are curated from data sources and presented on the nanomaterial details page, below. When available, the original publication link is provided so that you can verify the source data and access data that is outside of the NR MIAN. The NR Descriptor is a high level classification of the nanomaterial based on primary composition and shape.
Instance of Characterization (IOC) is a classification and description of the nanomaterial’s surrounding environment and time at which it was characterized. Each IOC at which the nanomaterial was characterized or studied is listed in the left side page navigation bar. You can click on an IOC in the navigation bar to see the curated data associated with that particular IOC.
Click the FIND SIMILAR NANOMATERIALS button to query nanomaterials that are at least 10% similar to this one. Similarity is determined using the Registry’s NANOMATERIAL SIMILARITY rules.
Compliance Levels are calculated using the Registry’s minimal information about nanomaterials (MIAN). More information can be found on the How Are Compliance Levels Calculated? or Minimal Information about Nanomaterials pages.
Data for physico-chemical characteristics (PCC) and interaction studies are curated when available. Physico-chemical characteristics are curated based upon the Registry’s Minimal Information about Nanomaterials (MIAN). Data from studies are contained on the Biological and Environmental Interaction tab and are summarized using four categories: General Study Details, Test Subject(s), Exposure Summary(s), and Endpoint(s).
ver 6.1.1