Curated Data based on Instance of Characterization
As Synthesized
 
  • Physico-Chemical Characteristics
  • biological interactions
  • Environmental interactions
Composition
graph
CORE (hover over circle for proportion of material)
arrow Proportion of Nanomaterial:    Not reported
Component 1
Material Type:
Fullerene/Carbon:

buckyball
Molecular Identity:
C
COATING (hover over circle for proportion of material)
arrow Proportion of Nanomaterial:    Not reported
Component 1
Molecular Identity:
N-succinimid Ester of Pyropheophorbide a

In Vitro Study 1

Test Subject
Test Subject 1:
Cell Culture Type: cultured cell line
Name: Jurkat E6.1
General Study Details
General:
Test Location: laboratory
Controls Used/Reported: Positive
Standard Protocol Used: Apo-ONE Homogeneous Caspase-3/7 Assay; Promega
Assay Used:
Manufacturer: Promega
Assay Name: Apo-ONE Homogeneous Caspase-3/7 Assay
Exposure Summary
General:
Method of Exposure: inoculation
Acute or Chronic Exposure: Acute exposure
Duration of Exposure / Incubation Time: 4 hours
Endpoint
Toxicity:
Cytotoxicity: Detected Quantitatively

In Vitro Study 2

Test Subject
Test Subject 1:
Cell Culture Type: cultured cell line
Name: Jurkat E6.1
Strain:
Cell Source:
General Study Details
General:
Test Location: laboratory
Controls Used/Reported:
Standard Protocol Used: XTT; Roche
Assay Used:
Manufacturer: Roche
Assay Name: XTT
Exposure Summary
General:
Method of Exposure: inoculation
Acute or Chronic Exposure: Acute exposure
Intended Dose:
Actual Dose:
Frequency of Dosage:
Duration of Exposure / Incubation Time: 4 hours
Duration Between Exposure and Sampling:
Duration Between Exposure and Measurement:
Endpoint
Toxicity:
Cytotoxicity: Detected Quantitatively
Mechanistic Analysis:
Gene Expression:
Protein Expression:
Enzyme Expression:
Cellular Uptake:
Cellular Uptake 1:
Biotransformation:
Biotransformation 1:
Other:
Metabolism:

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MIAN-specific data are curated from data sources and presented on the nanomaterial details page, below. When available, the original publication link is provided so that you can verify the source data and access data that is outside of the NR MIAN. The NR Descriptor is a high level classification of the nanomaterial based on primary composition and shape.
Instance of Characterization (IOC) is a classification and description of the nanomaterial’s surrounding environment and time at which it was characterized. Each IOC at which the nanomaterial was characterized or studied is listed in the left side page navigation bar. You can click on an IOC in the navigation bar to see the curated data associated with that particular IOC.
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Data for physico-chemical characteristics (PCC) and interaction studies are curated when available. Physico-chemical characteristics are curated based upon the Registry’s Minimal Information about Nanomaterials (MIAN). Data from studies are contained on the Biological and Environmental Interaction tab and are summarized using four categories: General Study Details, Test Subject(s), Exposure Summary(s), and Endpoint(s).
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