Term

Descriptor

Reference Organization

0D*

*Retiring Term Replaced with 3D (ISO descriptor)
A nanomaterial with three dimensions on the nanoscale. This includes nanospheres, nanocubes, quantum dots, etc.  

1D*

*Retiring Term Replaced with 2D (ISO descriptor)
A nanomaterial with two dimensions on the nanoscale.  This includes nanotubes, nanowires, etc.  

1D

(ISO descriptor) A material which has only one dimension in the nanoscale (between 1 nm and 100 nm). This includes nanofilms, nanoplates, etc. ISO

2D*

*Retiring Term Replaced with 1D (ISO descriptor)
A nanomaterial with one dimension on the nanoscale. This includes nanofilms, nanoplates, etc.  

2D

(ISO descriptor) A material which has two dimensions in the nanoscale (between 1 nm and 100 nm). This includes nanotubes, nanowires, etc. ISO

3D

(ISO descriptor) A material which has three dimensions in the nanoscale (between 1 nm and 100 nm).  This includes nanospheres, nanocubes, quantum dots, etc. ISO

agglomerate

Collection of weakly or loosely bound particles or aggregates or mixtures of the two in which the resulting external specific surface area is similar to the sum of the specific surface areas of the individual components ISO

aggregate

Strongly bonded or fused particles where the resulting external specific surface area might be significantly smaller than the sum of calculated specific surface areas of individual components ISO

aggregation/
agglomeration state

The extent to which a group of particles, affected by attractive forces, forms groups or clusters (A physico-chemical characteristic in the Registry minimal information about nanomaterials)

as processed

The instance of characterization that describes when a characterization has been performed on a nanomaterial after changing its physical state in some way (e.g., dispersion in a media or sonication)

as received

The instance of characterization that describes when a characterization has been performed on the nanomaterial in its native state after the scientist receives it from another lab or a manufacturer

as synthesized

The instance of characterization that describes when a characterization has been performed on the nanomaterial in its native state after synthesizing it

aspect ratio

Ratio of longest to shortest external particle dimension ISO

buckyball

A nanoparticle characterized by a spherical geometry and hollow interior that is comprised of 60 carbon atoms NCI Thesaurus

carbon nanotube

Nanotube formed of carbon ISO

coating*

*Retiring Term Replaced with outermost shell
The outermost shell of a material

composition

Chemical information and crystal structure of the nanomaterial (A physico-chemical characteristic in the Registry minimal information about nanomaterials)

core

The innermost element(s) or compound(s) in a nanomaterial

DWCNT

[double-walled carbon nanotube] A multi-walled carbon nanotube composed of only two nested, concentric single-wall carbon nanotubes ISO

engineered nanomaterial

Nanomaterial designed for a specific purpose or function ISO

fate & transport

Chemical change (fate) and physical location change (transport) of a material after insertion into an environment U.S. EPA

fullerene

Molecule composed solely of an even number of carbon atoms, which form a closed cage-like fused-ring polycyclic system with 12 five-membered rings and the rest six-membered rings ISO

graphene

single layer of carbon atoms with each atom bound to three neighbors in a honeycomb structure ISO

graphically represented

The term used to describe when information is presented in an image from which numerical values are not readily extractable

graphite

allotropic form of the element carbon, consisting of graphene layers stacked parallel to each other in a three dimensional, crystalline, long-range order ISO

impurity

Unintended constituent present in a manufactured nano-object. It could originate from the starting materials or be the result of secondary or incomplete reactions during the production process. While the impurity is present in the final material, it is generally not considered to be intentionally added. ISO

incidental nanomaterial

Nanomaterial generated as an unintentional by-product of a process ISO

instance of characterization

General term describing the designations of "as received", "as synthesized", and "as processed" used to capture the conditions under which a nanomaterial exists when it undergoes physico-chemical characterization or is used in a study

manufactured nanomaterial

Nanomaterial intentionally produced for commercial purposes to have specific properties or specific composition ISO

matrix

The components of the sample other than the analyte (e.g. nanomaterial) IUPAC

mean aerodynamic diameter

The average particle diameter as calculated by particle behavior in air or viscous fluid

mean crystallite size

The average physical magnitude of an individual perfect crystal or region of regular crystalline structure in the substance of a material

mean diameter

The term used for an average particle diameter when the measurement method is unspecified

mean hydrodynamic diameter

The average particle diameter calculated by particle diffusion within a fluid

mean primary particle size

The average particle diameter of the primary particle, when the measurement method is unspecified

medium

A chemical or solution that enables the analysis of a nanomaterial of interest

MIAN

[minimal information about nanomaterials] A list of the specific data and metadata fields which are either known or highly suspected as impacting critically the interactions of nanomaterials with biological or environmental systems

molecular identity

A description of a material's chemical makeup using a unique identifier such as chemical name, SMILES formula, CAS #, or PubChem CID

MWCNT

[multi-walled carbon nanotubes] Carbon nanotube composed of nested, concentric or near-concentric graphene sheets with interlayer distances similar to those of graphite ISO

nanofiber

Nano-object with two similar external dimensions in the nanoscale and the third dimension significantly larger ISO

nanomaterial

Material with any external dimension in the nanoscale or having internal structure or surface structure in the nanoscale ISO

nanomaterial state

The physical state of material at its time of measurement ISO

nano-object

Material with one, two or three external dimensions in the nanoscale ISO

nanoparticle

Nano-object with all three external dimensions at the nanoscale ISO

nanoplate

Nano-object with one external dimension in the nanoscale and the two other external dimensions significantly larger ISO

nanorod

A solid nanofiber ISO

nanoscale

Size range from approximately 1 nm to 100 nm ISO

nanostructured material

Material having internal nanostructure or surface nanostructure ISO

nanotechnology

Application of scientific knowledge to manipulate and control matter in the nanoscale to make use of size- and structure-dependent properties and phenomena distinct from those associated with individual atoms or molecules or with bulk materials ISO

nanotube

A hollow nanofiber ISO

NF

Nanofiber

NP

Nanoparticle

NPl

Nanoplate

outermost shell

In a nanomaterial's composition, the constituents making up its surface layer

PCC

Physico-chemical characteristic(s)

PDI

(MW) The distribution of molecular mass in a given polymer sample - the weight average molecular weight divided by the number average molecular weight

PDI

(Size) A parameter calculated from a Cumulants analysis of the DLS-measured intensity autocorrelation function

pharmacodynamics

(Registry descriptor) The relationship between drug/particle concentration at the site of action and the resulting effect, including the time course and intensity of therapeutic and adverse effects

pharmacodynamics

(Merck descriptor) The study of the biochemical and physiological effects of drugs and their mechanisms of action The Merck Manual

physico-chemical characteristics

Physical and chemical characteristics reported in the MIAN

porosity

A measure of void spaces in a material

primary particle

The nonaggregated , source particle of a sample

proportion of coating

The relative amount of a particular substance that composes the coating of a nanomaterial

proportion of core

The relative amount of a particular substance that composes the core of a nanomaterial

proportion of nanomaterial

The relative amount of a particular substance that composes the overall nanomaterial sample, not including its matrix

proportion of shell

The relative amount of a particular substance that composes a shell of a nanomaterial

protocols and parameters

The procedural methods and settings used in an experiment

purity

(Registry descriptor)Amount of the intended substance within a manufactured material - Also includes identity and amount of any contaminants (A physico-chemical characteristic in the Registry minimal information about nanomaterials)

purity

(ISO descriptor) Amount of the intended substance within a manufactured material ISO

QD

Quantum dot

quantum dot

Crystalline nanoparticle that exhibits size-dependent properties due to quantum confinement effects on the electronic states ISO

raw data

The data collected from an instrument which have not been subjected to processing or any other manipulation

shape

A geometric description of the extremities of a nanomaterial (eg, 1D, 2D, 3D) along with the rigidity of its spatial arrangement, as represented in its external surface (A physico-chemical characteristic in the Registry minimal information about nanomaterials)

shell continuity

The degree of holes or defects in a shell

size

(Registry descriptor) The physical dimensions of a particle. For spherical particles, it is their diameter. For irregularly shaped particles it is the diameter of the equivalent sphere which has the same volume as a particle. Also includes physical state of the sample. (A physico-chemical characteristic in the Registry minimal information about nanomaterials) The Nanomaterial Registry's scope for the size PCC is broader than the ISO description

size

(ISO descriptor) The physical dimensions of a particle determined by specified measurement conditions ISO

size distribution

(Registry descriptor) A list of values or a mathematical function that defines the relative amounts of particles present, sorted according to size - modality, peak magnitude, minimum and maximum are included (A physico-chemical characteristic in the Registry minimal information about nanomaterials) The Nanomaterial Registry's scope for information is necessarily more specific that the ISO description

size distribution

(ISO descriptor) Refers to a group of particles of differing sizes. When a group of particles are of differing sizes, they might be described by particle size distribution ISO

SMILES

[simplified molecular input line entry specification] A line notation for describing the structure of chemical molecules using short ASCII strings

solubility

(Registry descriptor) The degree to which a material can be dissolved in another material so that a single, homogeneous, temporally stable phase results. Expressed as the categorization of a material as hydrophilic or lipophilic as well as P value and D value (A physico-chemical characteristic in the Registry minimal information about nanomaterials) The Nanomaterial Registry's scope for information is necessarily more specific that the ISO description

solubility

(ISO descriptor) The degree to which a material (the solute) can be dissolved in another material (the solvent) so that a single, homogeneous, temporally stable phase (a suspension down to the molecular level) results ISO

stability

The measure of a system is in its lowest energy state or chemical equilibrium with its environment (A physico-chemical characteristic in the Registry minimal information about nanomaterials)

surface area

(Registry descriptor) The quantity of accessible surface of a nanomaterial. Surface area is conventionally expressed as a mass specific surface area or as volume specific surface area where the total areal quantity has been normalized either to the sample's mass or to a volume. (A physico-chemical characteristic in the Registry minimal information about nanomaterials) The Nanomaterial Registry's scope includes nanostructured materials as well as nano-objects

surface area

(ISO descriptor) The quantity of accessible surface of a powdered sample when exposed to either gaseous or liquid adsorbate phase. Surface area is conventionally expressed as a mass specific surface area or as volume specific surface area where the total areal quantity has been normalized either to the sample's mass or to a volume. ISO

surface charge

Electric charge on a surface in contact with a continuous phase (A physico-chemical characteristic in the Registry minimal information about nanomaterials) ISO

surface chemistry

(Registry descriptor) Chemical nature, including composition, of the outermost layer of a nanomaterial (A physico-chemical characteristic in the Registry minimal information about nanomaterials) The Nanomaterial Registry's scope includes nanostructured materials as well as nano-objects

surface chemistry

(ISO descriptor) Chemical nature, including composition, of the outermost layers of the nano-object ISO

surface coverage level

The amount of a material's surface occupied by a particular substance

surface reactivity

(Registry descriptor) Includes chemical affinities and speeds of reaction (A physico-chemical characteristic in the Registry minimal information about nanomaterials) The Nanomaterial Registry recognizes that there are no standard methods for analyzing surface reactivity and therefore allows the reporting of surface reactivity in many ways at this time.

surface reactivity

(ISO descriptor) Measurement of reactivity of a material to the species to which it is reactive (such as reactive to water) and typically involves measuring products or by-products of that reaction ISO

SWCNT

[single-walled carbon nanotube] Carbon nanotube consisting of a single cylindrical graphene layer ISO

toxicity

Deleterious or adverse biological effects elicited by a chemical, physical, or biological agent U.S. EPA

transformation

The processes or mechanisms which contribute to the degradation (chemical and biological) of a nanomaterial in an environment

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